FAMHXPD

Table Description:

Detailed notes for this table are included below.

1.0 Description: Family History (PD)

View Source CRFs

1.0 CRFs: Click on any PAG_NAME link below to be taken to the CRF used in the PPMI 1.0 Study.

2.0 CRFs: Click on any PAG_NAME link below to be taken to a screenshot of how this eCRF is currently implemented in the PPMI 2.0 Study.

2.0 Data Dictionary

Table Constraints:

Missing Columns

ITM_NAME

DSCR_1.0

BIODAD

Biological Father

BIODADPD

Biological Father with PD

BIOMOM

Biological Mother

BIOMOMPD

Biological Mother with PD

FULSIB

Full Siblings

FULSIBPD

Full Siblings with PD

HAFSIB

Half Siblings

HAFSIBPD

Half Siblings with PD

KIDSNUM

How many children do you have

KIDSPD

How many children with PD

MAGPAR

Maternal Grandparents

MAGPARPD

Maternal Grandparents with PD

MATAU

Maternal Aunts and Uncles

MATAUPD

Maternal Aunts and Uncles with PD

PAGPAR

Paternal Grandparents

PAGPARPD

Paternal Grandparents with PD

PATAU

Paternal Aunts and Uncles

PATAUPD

Paternal Aunts and Uncles with PD

STAFFCD

Examiner

Details

This CRF was redesigned in PPMI 2.0 to simplify it and to take advantage of conditional logic to avoid errors.

ANYFAMPD

If the answer to this variable is No, then none of the PD questions for individual family members will be collected. This means that, unlike in 1.0, there may be null values instead of zeros in these columns.

BIOMOMPD, BIODADPD, MAGMOTHPD, MAGFATHPD, PAGMOTHPD, PAGFATHPD

These variables are represented as booleans in 2.0, but were continuous variables in 1.0. Additionally, any total number of family member question associated with these categories have been removed. The assumption is that the total number is always 1 for all these family members.

Family Member Sub-Divisions

The way in which different categories of family members are divided has changed between PPMI 1.0 and 2.0. A summary of how each category is captured is below:

Total

PD

Mother

1.0

BIOMOM

BIOMOMPD

2.0

BIOMOMPD

Father

1.0

BIODAD

BIODADPD

2.0

BIODADPD

Siblings

1.0

FULSIB

FULSIBPD

2.0

FULBRO

FULBROPD

FULSIS

FULSISPD

Half Siblings

1.0

HAFSIB

HAFSIBPD

2.0

MAHAFSIB

MAHAFSIBPD

PAHAFSIB

PAHAFSIBPD

Maternal Grandparents

1.0

MAGPAR

MAGPARPD

2.0

MAGMOTHPD

MAGFATHPD

Paternal Grandparents

1.0

PAGPAR

PAGPARPD

2.0

PAGMOTHPD

PAGFATHPD

Maternal Aunts and Uncles

1.0

MATAU

MATAUPD

2.0

MATAU

MATAUPD

Paternal Aunts and Uncles

1.0

PATAU

PATAUPD

2.0

PATAU

PATAUPD

Maternal Cousins

1.0

2.0

MATCOUS

MATCOUSPD

Paternal Cousins

1.0

2.0

PATCOUS

PATCOUSPD

Children

1.0

KIDSNUM

KIDSPD

2.0

KIDSNUM

KIDSPD

Future State

For the purpose of analytic utility, most of the missing variables have been marked as DERIVED. Though we are no longer directly capturing this information in PPMI 2.0, it can be easily derived from the data that we do have, or can be imputed with the assumption that all participants have one of each Mother, Father, and Maternal and Fraternal Grandmothers and Grandfathers.